Over the last ten years, Oracle Cancer Trust has granted over £5m in funding pioneering early-stage research projects. These have paved the way for larger clinical trials to take place to test new drugs, new treatments and new techniques to combat head and neck cancer.
Crucially, without the Oracle ‘seed’ research, these large trials would simply not have been possible; Oracle is filling a research gap. Currently, mainstream funding for head and neck cancer is less than 2% in UK, and in recent years has actually declined. This is even more alarming given it is now the sixth most common form of cancer with cases rising rapidly particularly in younger age groups due to the HPV virus.
Oracle currently supports research in these five areas:
Each Oracle research project is rigorously assessed by peer review and independently approved by the Oracle Research Committee. All committees at Oracle are voluntary and non-conflicted as outlined by The Association of Medical Research Charities (AMRC). As members of AMRC, Oracle adhere to their strict guidelines and protocols for reviewing and selecting research projects to fund.
AMRC have five principles of peer review, which must be implemented by member charities across funding for all types of medical research.
- Accountability: Charities must be open and transparent about their peer review procedures and publish details, including the names of members of scientific advisory panels or other decision-making bodies.
- Balance: Scientific advisory panels must reflect a fair balance of experience and scientific disciplines.
- Independent decision making: The scientific advisory panel must be independent of the charity's administrative staff and trustees.
- Rotation of scientific advisers: Scientific advisory panel members must have a fixed term of office and not have tenure.
- Impartiality: Scientific advisory panels must include a significant number of non-beneficiaries. There must be a conflict of interest policy and potential beneficiaries should not be present when decisions are made.
We support the principle of using animals in research when it is necessary to advance understanding of health and disease and to develop new treatments. This research only takes place where there is no alternative available. All AMRC member charities support this principle, as outlined in this statement.
In line with this we support the principle of the 3Rs to refine, reduce and replace the use of animals in research and take them into consideration during the application and review process.
Currently mainstream funding for head and neck cancer is less than 2% in UK
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Oracle Cancer Trust is a registered charity in England and Wales (1142037). A company limited by guarantee. Registered company in England and Wales (7125497). Registered address: 10 Parsons Green House, 27 Parsons Green Lane, London SW6 4HH.